Is Niacinamide Good for Your Skin? How this Ingredient Can Revolutionize Your Skincare Game |
Home>Discover Topics>Skin Care>Is Niacinamide Good for Your Skin? How this Ingredient Can Revolutionize Your Skincare Game

Is Niacinamide Good for Your Skin? How this Ingredient Can Revolutionize Your Skincare Game

Fact checked

By , Certified Pharmacotherapy Specialist, PharmD, MPH, BCPS

Last Updated on November 24th, 2023 / Published on August 21, 2023

Is Niacinamide Good for Your Skin? How this Ingredient Can Revolutionize Your Skincare Game

You’re not alone if you’ve struggled for years with skincare concerns such as acne, hyperpigmentation, or aging skin. In recent years, people who love skincare have been really excited about niacinamide. This vitamin is also called vitamin B3 or nicotinamide.

This wonder ingredient has been the subject of various studies and has proven to offer remarkable benefits for the skin. Niacinamide could be the game-changer you’ve been searching for.

Let’s delve into the fascinating world of niacinamide. We’ll explore how it can revolutionize your skincare game.

Niacinamide for Skincare

Niacinamide is a naturally occurring compound and an essential nutrient. An essential nutrient is a substance your body needs to stay healthy and function properly.

Since your body can’t produce enough of these essential nutrients by itself, you must get them from food. You’ll find niacinamide in various plant and animal sources, including:

  • Meats: Chicken, turkey, beef, pork, and organ meats like liver
  • Fish: tuna, salmon, and sardines
  • Legumes and Nuts: peanuts, lentils, and beans
  • Whole Grains: wheat, barley, and rice
  • Vegetables: Mushrooms, avocados, potatoes, and green leafy vegetables


Your body also synthesizes niacinamide to make sure you have enough. It does this by breaking down niacin (also known as vitamin B3), another essential vitamin found in food. Your body converts niacin into niacinamide because it needs niacinamide to help produce energy and repair DNA.

Similarly, your body converts tryptophan, another essential amino acid found in food, into niacinamide. But, tryptophan is not the main source of niacinamide. You get most of your niacinamide directly from your food or supplements.

Many skin care products use synthetically produced niacinamide. It comes in various forms that let you choose the best product for your skin needs.

Choosing the form of niacinamide for your skin type and skincare goals is essential. Reputable brands contain an adequate concentration of niacinamide.

8 Niacinamide Skincare Benefits

Benefits of Niacinamide


  1. Enhances Skin Barrier Function: Niacinamide makes your skin’s natural barrier stronger. It helps create ceramides. These ceramides keep moisture in. They also protect your skin from outside things that can stress it out.
  2. Moisturizes Skin: Niacinamide has hydrating properties that improve skin moisture levels.
  3. Helps Manage Oily Skin: It regulates the production of sebum (your skin’s oily secretions). This is useful for individuals with oily skin.
  4. Minimizes Pore Appearance: It helps tighten pores, leading to smoother-looking skin.
  5. Protects Against Sun Damage: Niacinamide helps protect your skin from harmful sun rays. As a result, your skin won’t get older too quickly.
  6. Reduces Inflammation: Its anti-inflammatory properties help soothe and calm irritated or inflamed skin. This makes it beneficial for sensitive or acne-prone skin.
  7. Fades Hyperpigmentation: Niacinamide helps reduce dark spots and even out skin tone. It does this by regulating melanin production.
  8. Reduces Fine Lines and Wrinkles: Niacinamide helps keep collagen in your skin. This can make fine lines and wrinkles look less noticeable.

Using niacinamide leaves your skin healthy, radiant, and full of beauty and confidence.

How Niacinamide Works on the Skin

At this point, we know niacinamide helps improve your skin’s look, feel, and health. But how does it work?1-4

  • Boost Cellular Energy: Niacinamide is essential for making energy in cells. It’s a key part of things needed in energy-making processes.
  • Help DNA Repair: Niacinamide works with proteins and enzymes that fix DNA. This ensures the DNA in cells stays stable and not damaged.
  • Preserve Collagen: Niacinamide preserves collagen, an important protein for firm and stretchy skin. This helps your skin look younger.


Is Niacinamide Good for Your Skin? Examining the Evidence

Scientific studies5 show that niacinamide is safe. They also show that niacinamide improves different skin problems without many side effects. Here are some studies showing niacinamide is good for your skin.

Niacinamide helps treat acne

In a review of several studies,5 niacinamide-based products improved acne compared to the baseline. When researchers compared niacinamide to other standard acne treatments, it performed similarly. Overall, study participants tolerated niacinamide without any major side effects.

Niacinamide helps prevent signs of aging

Niacinamide has antioxidant properties that help stop signs of aging. This is because it protects against things in the environment and inside our bodies that can age the skin.

In one study,6 researchers exposed participants to oxidative stress from environmental pollutants. Oxidative stress happens when there are too many harmful molecules and not enough protecting antioxidants in your body. They found that niacinamide helps protect skin cells from the harmful effects of oxidative stress.

Another study7 found that regular application of 5% topical niacinamide reduces uneven skin tone in people aged 40-60. Participants also saw reduced wrinkling, red blotchiness, and hyperpigmented spots. The researchers saw similar results with niacinamide-based products compared to standard treatments.5

While experts generally like niacinamide, everyone’s skin is different, so the results can vary from person to person. To find the right niacinamide product for you, talk to a dermatologist. They can give you personalized advice and help you pick the best niacinamide product that suits your skin’s needs.

Incorporating Niacinamide into Your Skincare Routine

Finding the Right Niacinamide Skincare Products

Choosing the right niacinamide skincare product can be tricky. This is because there are so many varieties.

  • Niacinamide Concentration: Check the percentage of niacinamide; higher concentrations (2%-5%)8 may work better for specific skin concerns.
  • Skin Type: Select a lightweight serum for oily or acne-prone skin or cream for dry skin.
  • Complementary Ingredients: Look for products with hyaluronic acid, vitamin C, or peptides. These ingredients enhance niacinamide’s effects.
  • Potential Irritants: Avoid products with irritants or allergens. Especially if you have sensitive skin.
  • Reviews and Reputation: Read reviews from trusted sources to gauge product effectiveness.

Perform a patch test before using any new product. Also, since your skin may have specific needs, ask your dermatologist first for personalized advice.

Complementing Niacinamide with Other Skincare Ingredients

To create a comprehensive skincare routine, combine niacinamide with other beneficial ingredients.

Hyaluronic acid and niacinamide

Teaming niacinamide with hyaluronic acid boosts hydration as it locks in moisture.

Vitamin C and niacinamide

Vitamin C is an antioxidant that makes your skin stronger against damage. It helps your skin look brighter and can make fine lines less noticeable.

Exfoliants and niacinamide

Using niacinamide with gentle exfoliants like AHAs or BHAs can improve your skin texture.

When to Use Niacinamide in Your Skincare Routine

Daytime and Nighttime Applications

Niacinamide offers multiple benefits for both daytime and nighttime use. During the day, apply it after cleansing and toning but before moisturizing and sunscreen. This order shields the skin from environmental stressors and improves oily skin.

At night, include it in your routine after cleansing, toning, and using other active ingredients like retinoids.

The frequency of use depends on the concentration and your skin’s tolerance. Once or twice daily is sufficient for most.

Follow the product’s instructions. Start with a lower frequency if you’re new to niacinamide.

Combining Niacinamide with Sunscreen and Other Products

Here are some tips for using niacinamide with other products:

  • Niacinamide and Sunscreen: First, put on niacinamide to help protect your skin against damage. Then, use sunscreen to guard your skin from harmful sun rays.
  • Niacinamide and Vitamin C: These antioxidants work well together. Use vitamin C in the morning and niacinamide in the evening to avoid issues.
  • Niacinamide and Retinoids: Niacinamide can reduce irritation from retinoids. Use niacinamide in the morning and retinoids at night.
  • Niacinamide and Hyaluronic Acid: First, apply niacinamide. Then, apply hyaluronic acid to lock in moisture.

By figuring out how to mix niacinamide with other skincare stuff, you can get the most from its benefits.

Potential Side Effects and Precautions

While niacinamide has many benefits for the skin, it’s important to be aware of potential side effects.

Allergic reactions, though rare, can cause redness, itchiness, or mild burning. To avoid issues, do a patch test first, especially if you have sensitive skin.

Niacinamide usually goes well with other skincare stuff. But be careful when you use it with things like acids or retinoids. Using it in this way might cause skin color changes.

If you want to start using niacinamide, talk to your skin or regular doctor first. This is especially important if you have certain skin problems.

Niacinamide Cream for Face: A Deep Dive

Exploring Niacinamide Cream Formulations: Creams, Serums, and Lotions: Which is Best?

So, which formulation of niacinamide is best? With so many on the market, how do you choose what works for your skin type? Some standard options include:

Niacinamide Creams: Creams are thicker and provide a moisturizing effect, locking in moisture. Creams are suitable for those with dry or normal skin types.

Niacinamide Serums: Serums are light and soak into your skin fast. This lets them have a stronger amount of niacinamide without being heavy like a cream. Serums are beneficial for all skin types, including oily and combination skin.

Niacinamide Lotions: Lotions are lighter than creams but thicker than serums. They offer a balanced level of hydration and work for various skin types.

Niacinamide Toners: Toners are watery solutions. They are usually applied with a cotton pad or spritzed onto the skin. They’re suitable for adding niacinamide into your routine without using heavier products.

Niacinamide Face Masks: Some face masks contain niacinamide as a key ingredient for skin nutrients. For an extra skincare treat, use these masks occasionally.

Niacinamide Cream DIY Recipes and Tips

Cream For Niacinamide

If you like making your skincare products, you can try DIY niacinamide recipes. But take proper precautions.

Use high-quality niacinamide from trusted suppliers. Keep the concentration at 2-5% to avoid irritation.

Be careful with other strong ingredients like acids or retinoids. Make sure to keep everything clean and sterilized when making and storing your DIY cream. Keep it in a dark, airtight container to protect its potency.

Remember, DIY skincare has some risks, and not all homemade products may work well. If you want a safer choice, consider using skincare products with niacinamide from well-known brands. Such brands have done research to back them up.


Niacinamide is a powerful skincare ingredient with various benefits. These include strengthening the skin’s barrier and reducing inflammation.

Niacinamide works well for different skin types. However, individual reactions can vary. So, consult a dermatologist or doctor before using niacinamide in your routine. They can provide personalized advice and ensure it’s safe for you. With their guidance, you can enjoy the full potential of niacinamide, achieving healthy and radiant skin.


  1. Snaidr VA, Damian DL, Halliday GM. Nicotinamide for photoprotection and skin cancer chemoprevention: A review of efficacy and safety. Exp Dermatol. 2019 Feb;28 Suppl 1:15-22.
  2. Park J, Halliday GM, Surjana D, et al. Nicotinamide prevents ultraviolet radiationinduced cellular energy loss. Photochem Photobiol. 2010 Jul-Aug;86(4):942-8.
  3. Fania L, Mazzanti C, Campione E, Candi E, Abeni D, Dellambra E. Role of Nicotinamide in Genomic Stability and Skin Cancer Chemoprevention. Int J Mol Sci. 2019;20(23):5946. Published 2019 Nov 26. doi:10.3390/ijms20235946
  4. Boo YC. Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation. Antioxidants. 2021; 10(8):1315.
  5. Kalasho BD, Minokadeh A, Zhang-Nunes S, et al. Evaluating the Safety and Efficacy of a Topical Formulation Containing Epidermal Growth Factor, Tranexamic Acid, Vitamin C, Arbutin, Niacinamide and Other Ingredients as Hydroquinone 4% Alternatives to Improve Hyperpigmentation: A Prospective, Randomized, Controlled Split Face Study. J Cosmet Sci. 2020;71(5):263-290.
  6. Zhen AX, Piao MJ, Kang KA, et al. Niacinamide Protects Skin Cells from Oxidative Stress Induced by Particulate Matter. Biomol Ther (Seoul). 2019;27(6):562-569. doi:10.4062/biomolther.2019.061
  7. Bissett DL, Miyamoto K, Sun P, Li J, Berge CA. Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin. Int J Cosmet Sci. 2004;26(5):231-238. doi:10.1111/j.1467-2494.2004.00228.x
  8. Voegeli R, Guneri D, Cherel M, Summers B, Lane ME, Rawlings AV. Topical niacinamide enhances hydrophobicity and resilience of corneocyte envelopes on different facial locations. Int J Cosmet Sci. 2020;42(6):632-636. doi:10.1111/ics.12666


Was this Article Helpful?
share this page
Join our community of health and wellness enthusiasts today !!

Whether you're looking for new workout ideas, healthy recipes, or information on sexual health, we've got you covered

Written By
Zuri Hawkins Jarret

Certified Pharmacotherapy Specialist, PharmD, MPH, BCPS
Written By

Certified Pharmacotherapy Specialist, PharmD, MPH, BCPS
  • Zuri Hawkins-Jarrett graduated with her doctorate in pharmacy from The University of Georgia College of Pharmacy. She completed her residency training with Piedmont Columbus Regional in ambulatory care.
  • Zuri also has a Master of Public Health degree from Emory University with a focus on Prevention Science. She has a passion for pharmacy and public health to help those in her community diagnosed with chronic conditions.

The content provided on this site is for informational purposes only and is not intended as medical advice, diagnosis, or treatment. Read More.

Join our community of health and wellness enthusiasts today !!

Whether you're looking for new workout ideas, healthy recipes, or information on sexual health, we've got you covered

Join our community of health and wellness enthusiasts today !!

Whether you're looking for new workout ideas, healthy recipes, or information on sexual health, we've got you covered